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Doctor's Assessment Included

Every result includes a professional assessment from a BIG-registered doctor. For treatment decisions, discuss your results with your GP.

STD

HIV 1/2 Antibody + p24 Antigen

The HIV Combo test is a fourth-generation test that detects both HIV p24 antigen and HIV antibodies simultaneously. This dual approach enables earlier detection compared to antibody-only tests, typically within two to six weeks after exposure.

What It Measures

This test simultaneously screens for two markers: the HIV p24 antigen, which is a viral protein produced early in infection, and antibodies that the immune system generates in response to HIV. By detecting both, the test covers different stages of the infection timeline.

The p24 antigen is typically detectable before antibodies develop, which means this combination test can identify HIV infection during the acute phase when viral load is high and transmission risk is greatest.

Why It Matters

Early HIV detection is critical for both individual health and public health. Starting antiretroviral therapy promptly after diagnosis can significantly improve long-term health outcomes and reduce the risk of transmitting the virus to others.

With modern treatment, people living with HIV can achieve an undetectable viral load, meaning the virus cannot be transmitted sexually. Early testing is a key step toward accessing this life-changing treatment.

When to Test

Testing is recommended for anyone who is sexually active, particularly those with new or multiple partners. It is also advised after potential exposure events such as unprotected sexual contact, needle sharing, or occupational exposure.

The window period for this test is typically two to six weeks. For the most reliable results, testing at least four weeks after potential exposure is recommended, with a follow-up test at twelve weeks for definitive confirmation.

Recommendations

Male

If Low

Non-reactive result indicates no HIV infection detected. Continue safe practices and regular testing if at risk.

If High

Reactive result requires immediate confirmation testing and consultation with an infectious disease specialist.

Female

If Low

Non-reactive result indicates no HIV infection detected. Continue safe practices and regular testing if at risk.

If High

Reactive result requires immediate confirmation testing and consultation with an infectious disease specialist.

Lifestyle Tips

Consistent condom use is one of the most effective ways to reduce HIV transmission risk. If you are at higher risk, discuss pre-exposure prophylaxis (PrEP) with your healthcare provider as an additional prevention strategy.

Regular HIV testing normalises screening as part of routine health care. Knowing your status empowers you to make informed decisions about your health and the health of your partners. Never share needles or other injection equipment.

Frequently Asked Questions

What is the window period for the HIV Combo test?
The window period is typically two to six weeks after exposure. The p24 antigen component can be detected as early as two weeks, while antibodies may take longer to develop. For definitive results, testing at four weeks with confirmation at twelve weeks is recommended.
What happens if my HIV Combo test is positive?
A positive result on the combo test is considered preliminary and will be confirmed with additional testing, such as a Western blot or HIV RNA test. Your healthcare provider will guide you through confirmation testing and discuss next steps, including treatment options.
Is HIV testing confidential?
Yes, HIV testing is conducted with strict confidentiality. Your results are protected health information. Testing is a responsible and routine part of health care, and there is no judgment associated with seeking a test.

Test Products

This marker is included in the following test panels.