Home
/
Markers
/
Serology
/
EBV EBNA IgG

EBV EBNA IgG: What a Positive Result Means

An EBV EBNA IgG test detects IgG antibodies against the Epstein-Barr nuclear antigen (EBNA). A positive result typically indicates a past EBV infection, as EBNA antibodies develop weeks to months after the initial infection and usually persist for life.

Doctor's Assessment Included

EBV EBNA IgG: what this test measures

This test detects the presence of IgG antibodies directed against the Epstein-Barr nuclear antigen in your blood. EBNA antibodies develop during the convalescent phase of EBV infection, typically six to eight weeks or later after the onset of symptoms. Their presence generally indicates that the acute phase of infection has passed.

EBV EBNA IgG: why this value matters

EBV EBNA IgG testing helps distinguish between a past and a recent EBV infection. Since EBNA antibodies typically do not appear during the acute phase, their presence suggests that the infection occurred in the past. This differentiation can be important for clinical assessment, particularly when evaluating unexplained fatigue or other symptoms. Results should be interpreted by a healthcare professional.

EBV EBNA IgG: how the blood test works

Referral: No GP referral needed. After the order we arrange the referral through ZorgDomein, within one business day; orders after 17:00 or at the weekend start on the next business day. ZorgDomein emails a barcode, and that barcode is what the draw site needs.
The draw: A blood draw from a vein in the arm, at a partner laboratory's draw site. No home kit, no finger prick.
Which test: on its own €36,-
Where: 650+ draw sites run by independent laboratories across the Netherlands. Draw sites

EBV EBNA IgG: when is testing worthwhile?

Testing may be recommended when investigating symptoms such as prolonged fatigue, swollen lymph nodes, or recurrent sore throat, particularly when differentiating between a past and recent EBV infection is clinically relevant. Consult a healthcare professional for guidance.

EBV EBNA IgG: lifestyle and this value

EBV is spread through saliva and close personal contact. Maintain good hygiene practices and avoid sharing drinks, utensils, or personal items. Support your immune system with a balanced diet, regular exercise, adequate sleep, and effective stress management. If you experience persistent fatigue, consult a healthcare professional.

EBV EBNA IgG: frequently asked questions

What does a negative EBV EBNA IgG result mean?

A negative EBNA IgG result may indicate that you have never been infected with EBV, or that you are in the early stages of an acute infection before EBNA antibodies have developed. Your healthcare professional may recommend additional EBV antibody tests for a complete assessment.

Can EBV reactivate after the initial infection?

Yes, EBV remains dormant in the body after the initial infection and can reactivate, particularly during periods of immune suppression. Reactivation is usually asymptomatic in healthy individuals but may cause symptoms in immunocompromised people. Consult a healthcare professional if you have concerns.